Categories: Anxiety and Stress

CBDA for Depression

CBDA for Depression

Mental wellness can mean a lot of different things, and often, when our mood swings we may not even realize it if we are busy or distracted. 

Unfortunately, this is also true for depression, and while some people may be diagnosed, many are also under-diagnosed or just need relief in their daily activities.

One such solution to provide relief that has been gaining attention in recent years is CBDA for depression. CBDA is an acidic cannabinoid found in the cannabis sativa plant and has superior absorption and serotonin effects than all the other cannabinoids.

Let’s take a closer look at CBDA and its potential as a natural solution for mental health, specifically for depression. Then, we’ll introduce you to the best selection of safe, effective CBDA products for sale right here at Natural Dos.

Overview of Depression

Depression is a complex and multifaceted mental health condition characterized by persistent feelings of sadness, hopelessness, and a lack of interest or pleasure in activities. It can significantly impact daily functioning and quality of life, affecting one’s emotions, behavior, and physical health. 

Symptoms may include changes in appetite or weight, sleep disturbances, fatigue, difficulty concentrating, and thoughts of self-harm or suicide. The causes of depression are varied and can involve a combination of genetic, biological, environmental, and psychological factors.

Advancements in our understanding of depression have revealed the role of neurotransmitters – chemicals that transmit messages in the brain – and their impact on mood regulation. 

Traditional treatments typically involve psychotherapy, antidepressant medications, or a combination of both. However, there is growing interest in alternative therapies, including the use of cannabinoids such as Cannabidiolic Acid (CBDA). 

So, let’s turn our attention to how this natural treatment method could be the key to restoring a sense of hope and happiness in your life.

Is There Really Evidence Supporting the Use of CBDA For Depression?

First, what is CBDA? Also known as cannabinolic acid, it is a precursor to CBD, which is created when CBDA is exposed to high heat. Both CBDA and CBD cannabinoids are non-psychoactive compounds found in cannabis. They are known for a wide variety of medicinal properties.

While CBD has been extensively studied, CBDA is relatively less known. However, recent pre clinical evidence revealed CBDA as a natural option for treating mental health conditions such as depression. CBDA for anxiety induced by social phobia is another common use case.But, let’s narrow our focus on the CBDA benefits to look specifically at depression.

CBDA, the endocannabinoid system, and depression

CBDA works by interacting with the endocannabinoid system. This system is responsible for regulating various physiological functions. These functions include mood, appetite, and sleep. It’s believed that CBDA can help to modulate the activity of this system. And in turn, it can possibly help to improve mood and reduce symptoms of depression.

Additionally, CBDA has anti-inflammatory and antioxidant properties. Studies indicate that CBDA may help to reduce inflammation in the brain. Since inflammation in the brain is thought to contribute to the development of depression, it suggests that there may be multiple methods by which CBDA can have therapeutic potential.

CBDA and serotonin levels

Additionally, a systematic review regarding CBDA has shown that it can activate the serotonin receptor 5HT1A. Serotonin is a neurotransmitter that plays a key role in regulating mood. By increasing serotonin levels in the brain, CBDA may be a potential treatment for depressive symptoms. This

CBDA particularly helps to improve mood and reduce anxiety levels. It may also be helpful for conditions potentially related to depression such as chronic pain. CBDA is also showing promise as a natural alternative for treating anxiety, PTSD, and other mental health conditions.

Depression and predisposition

Depression has many different components that can contribute to the mental health of a patient. Often, these can be a combination of environmental cues, like poor nutrition and exercise, drugs, and more. But there also seems to be a genetic component.

These factors are often enhanced for those who have major depressive disorder or mixed social anxiety disorder. Therefore, it’s always best to speak with a healthcare professional before taking any supplement containing CBDA or any other cannabinoid as a treatment for depression.

CBDA and legal definition

In 2018, the FDA approved that most of the hemp plant was removed from the Controlled Substances Act. This law makes THC the only compound from the hemp plant that remains federally illegal if over a concentration of 0.3% by weight. The legality of CBDA is legal in all states and is not considered a controlled substance.

The FDA has not approved nonprescription CBDA products, like CBDA oil. Therefore, it’s important to make sure any products you buy are labeled accurately.

Why Use CBDA for Depression Over Traditional Medications and Treatments?

The cannabis sativa plant has long been used for its mental health properties, and with modern science, we are now able to capture those critical compounds that are known to provide those beneficial effects.

But, what exactly makes using CBDA for depression so enticing? Why use nature’s goodness instead of the traditional treatment methods doctors prescribe? Let’s take a look below…

Serotonin and depression, the changing landscape

Serotonin is a critical neurotransmitter involved in many of the most basic brain activities. Because the nervous system is so complicated, it is often difficult to tease apart the effects of a single neurotransmitter vs its effect in combination with all the others.

When it comes to depression, most of the early research suggests that there is a role for serotonin. A lot of the conventional therapies, such as elective serotonin reuptake inhibitors (SSRIs), that have come out of this observation are based on the serotonin model of depression.

However, this is being called into question as multiple large studies on serotonin metabolites have been inconclusive.

However, there is good clinical evidence that SSRIs have an effect on some people with depression, despite new evidence that the serotonin levels may not be that different between healthy controls and those with depression.

Side effects of SSRIs

For those taking SSRIs, there can be significant differences in side effects, but some of the most commonly reported ones are:

  • Drowsiness
  • Dry mouth
  • Insomnia
  • Headache
  • Sexual dysfunction
  • Appetite

Important: while SSRIs are not thought to be addictive, many people report withdrawal symptoms when they stop taking their medications.

As referenced above, CBDA can also interact with 5HT1A, a serotonin target for SSRIs. However, it does not have the withdrawal effects that SSRIs are known to have. This may be due to the other cannabinoid receptors that it also interacts with. There are no CBDA side effects to be worried about. 

CBDA and mood

There are many surveys that show the majority of respondents reported they felt better after CBDA and CBD treatment.

Another important difference is the potential anti-anxiety effects of CBDA. While cannabinoid users typically report improved relaxation, this also includes better sleep, and the potential for lower inflammation in many cases.

CBDA is generally considered to be well-tolerated and has fewer reported side effects. However, more research is needed to fully understand the safety and efficacy of CBDA compared to traditional antidepressant medications.

Tips on Using CBDA to Combat Depression

If you plan on taking CBDA for depression, start with a lower CBDA dosage of 25mg to 50mg per day. Since everyone is a little different in how their body handles cannabinoids, you want to make sure it works for you before increasing a dose.

The effects of CBDA can last a while depending on your individual makeup. There are number of factors that play into this:

  • Body weight
  • Liver metabolism
  • How often you take it and the dose
  • The state of your endocannabinoid system
  • Other medications that you are on

If you are on other medications, we recommend speaking with your healthcare provider before trying CBDA or other hemp-derived CBD products.

How often should I take CBDA?

While this may vary for the individual, many customers who take CBDA for its relaxing benefits, report taking CBDA two to three times a day. This is usually in the morning and then again later in the afternoon.

How do I know if CBDA is working?

Keeping a journal of your day, and how you feel is one of the best ways to track changes in your mood and mental wellbeing over time.

This method is best done by keeping a small journal next to your bed to make it as easy as possible to be consistent

Choosing the Right CBDA Products for Your Battle Against Depression

When purchasing CBDA products, always be sure to check for third party testing that will be reported as a certificate of analysis (CoA). This should show the potency of the product (the amount of cannabinoids), and if there is any contamination in the product.

As we said from the start, your search for the finest CBDA products ends here at Natural Dos. We’re pioneering the CBDA market and leading the charge with our innovative approach to extraction, which preserves as much CBDA as possible to ensure you’re getting the best value.

We prioritize peak CBDA absorption, as we know that part of the problem with traditional CBD products is their low absorption rates. Our products absorb up to 1,000% better!

Plus, you gain access to a wide variety of consumption methods to choose from. Try our classic CBDA gummies for a tasty treat, or use our CBDA oil to titrate your dosage to perfection. We also have CBDA mints, CBDA capsules, and CBDA tinctures, all of which are extracted and manufactured to the highest quality standards.

With our 100-day money-back guarantee, you can feel confident ordering your products today and seeing what a difference they make in your depression. So, what are you waiting for? Shop today!

More ways to cope with depression

Coping with depression involves a multi-faceted approach that can include lifestyle changes, therapeutic techniques, and alternative treatments beyond CBDA. Here are several strategies that can help manage symptoms of depression:

  • Psychotherapy: Talking therapies like cognitive-behavioral therapy (CBT), interpersonal therapy (IPT), and dialectical behavior therapy (DBT) can be very effective in treating depression by addressing negative thought patterns and improving coping skills.
  • Regular Exercise: Physical activity can boost mood and reduce symptoms of depression due to the release of endorphins, which are natural mood lifters. Aim for at least 30 minutes of moderate exercise most days of the week.
  • Healthy Diet: Eating a balanced diet rich in fruits, vegetables, whole grains, and lean protein can support overall health and affect mood positively. Some studies suggest that diets with a high intake of omega-3 fatty acids and lower in processed foods might be beneficial for those with depression.
  • Adequate Sleep: Sleep and mood are closely connected. Establishing a regular sleep routine and ensuring you get enough rest can help manage depression symptoms.
  • Mindfulness and Meditation: These practices can help individuals focus on the present moment and become more aware of their thoughts and feelings without becoming overwhelmed by them.
  • Social Support: Building and maintaining a strong support network of friends, family, or support groups can provide emotional support and reduce feelings of isolation.
  • Stress Reduction Techniques: Learning and practicing stress management techniques such as deep breathing, progressive muscle relaxation, or yoga can help alleviate tension and improve emotional well-being.
  • Light Therapy: For those with seasonal affective disorder (SAD), exposure to bright light can help regulate mood.
  • Creative Outlets: Engaging in creative activities like art, music, or writing can be therapeutic and offer a means of expression and distraction.

A word on drug-drug interactions

Many compounds are metabolized by the liver, and this includes CBDA, CBD and many medications like SSRIs. When too many compounds are being metabolized in the liver by the same enzymes, sometimes you can get liver toxicity.

While clinical trials on CBDA side effects have not been performed, CBD at high doses was found to be associated with an increase in liver enzymes for epileptic patients. These patients were taking CBD in doses over 1000mg per day and were on multiple medications.

If you are on multiple medications, please speak with your healthcare provider before trying CBDA. But, don’t be afraid to harness the power of the best CBDA tincture or other products at your disposal today at Natural Dos. Relief is just a few clicks away!

Closing Thoughts on CBDA for Depression

While there are many treatment options available for depression, a natural alternative like CBDA may provide some relief. Much of the research on CBDA for depression is in the preclinical stage, but many users report improvement in mood.

It’s still important to note that the safety and efficacy of CBDA for treating depression have not been fully established. Additionally, CBDA is not regulated by the Food and Drug Administration (FDA). And just like any other supplement, it may cause side effects if not taken with precaution.

It’s best to consult with a healthcare professional to determine if CBDA is appropriate for you. They will also discuss with you the potential risks and benefits.

Learn more about CBDA oil benefits in our blog. We have resources like CBDA for nausea, CBDA for anxiety, CBDA for pain, CBDA vs CBD, how to decarboxylate CBDA, CBDA flower, CBDA vs CBG, does CBDA get you high, CBDA vs CBDV, and more.

Otherwise, it’s time to get your hands on the best CBDA oil or the tastiest, most potent gummies on the market. Experience for yourself how CBDA for depression can turn your life around and reframe the way you view everyday life!

Colin Reily PhD

Article scientifically and medically reviewed for accuracy. Colin Reily is a Professor of Medicine and scientific consultant.

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Colin Reily PhD

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