Categories: Sleep

CBDA For Sleep: Can This Cannabinoid Help You Overcome Insomnia?

CBDA For Sleep: Can This Cannabinoid Help You Overcome Insomnia?

Tossing and turning through sleepless nights? You’re not alone. Many struggle with restless minds and bodies, desperately seeking a night of peaceful slumber. 

Enter CBDA sleep oil, a natural ally in the battle against insomnia and disrupted sleep patterns. This article delves into how you can harness the power of CBDA for sleep, particularly in its tincture form. This mysterious little cannabinoid could be the key to unlocking restful nights and rejuvenating mornings. 

We’ll explore the science behind its effectiveness, debunking myths and highlighting facts, guiding you to a potential solution for those elusive Zs. 

If you want to skip to the good part where you’re no longer battling restless nights, discover the finest CBDA for sale at Natural Dos today! In the meantime, we’ll discuss the need for quality sleep in the first place.

The Importance of a Good Night’s Sleep

Sleep is critical to health, but almost almost a third of Americans report not getting less than 6 hours of sleep a night. Most sleep experts suggests that on average you need to get a minimum of 7 hours of sleep, and depending on the individual, you may need up to 9 hours of sleep.

The quality of sleep is also important, and to get restorative sleep, deep sleep and REM sleep are required. Deep sleep (also termed non-REM) comes first and is associated with bodily restoration, such as higher blood flow, cellular repair, and fresh fluids to the brain. REM (rapid eye movement) sleep is associated with dreaming, and the processing and storage of memories. 

How Anxiety and Stress Affect Sleep

Poor sleep is often associated with symptoms of stress and anxiety. Too much anxiety at bedtime can disrupt sleep, and poor sleep itself can cause anxiety. About a third of patients with insomnia report anxiety issues. Clinical diagnostic symptoms for generalized anxiety disorder and posttraumatic stress disorder both use sleep disorder as a category for diagnosis.

In a recent study of insomnia and anxiety disorders, they found that in about 18% of patients insomnia appeared before the onset of anxiety. However, in around 44% of patients, anxiety symptoms were present before insomnia conditions occurred, with the remaining showing that symptoms of both were present at the same time.

Stress is largely dependent on the activation of the HPA (hypothalamic-pituitary-adrenal) axis, the system responsible for the fight or flight response when we are confronted with a threat. While this is helpful when a physical threat is present, activation of HPA during everyday events, such as work deadlines and road rage, can lead to chronic stress and cortisol (stress hormone) production. Excessive activation of the HPA axis and elevated levels of cortisol are classic indicators of stress and may have significant impacts on some of the sleep cycles.

Research suggests that the endocannabinoid system is tightly integrated with mood and psychological state, and may play critical roles in anxiety, stress, and depression through the HPA axis. Early research suggests that modulating the endocannabinoid system may provide a route to sleep aid, highlighting the potential benefits of how CBDA and CBD helps sleep. Additionally, long-term analysis of endogenous endocannabinoids and depressive symptoms were found to be significantly inversely correlated, more than cortisol. This suggests that lower levels of endocannabinoids may predict certain states of depression, further evidence that modulating the endocannabinoid system could have mental health benefits.

If you are suffering from chronic stress and anxiety, it is important to talk with a medical professional about the best ways to approach it.

A Brief Overview of CBDA

Now, what is CBDA? Most people have heard of CBD oil, but are not familiar with the more powerful CBDA (cannabidiolic acid) that is the naturally occurring cannabinoid in the hemp plant. The cannabis plant has over 100 different cannabinoids that are naturally occurring before processing.

During conventional purification of hemp oil, CBDA is converted to CBD through a process called decarboxylation. Only recently has Natural Dos created a new technology to purify all the acidic cannabinoids from the hemp plant without decarboxylation. Learn how to decarboxylate CBDA in our blog.

Another form of hemp extract is using a press, which creates a raw form of oil. This is another great method to extract various cannabinoids in their naturally occurring acidic state.

Examining the Role of CBDA for Sleep

Most people are surprised at how well CBDA vs CBD can be used to help with anxiety and stress. It may be that some of the underlying factors that are causing sleep disturbances are associated with anxiety and stress at night.

There are many studies showing the potential benefits that cannabinoid oil supplementation can have on sleep quality. For example, a pre-clinical study in vivo found that CBD was able to block anxiety-induced REM sleep disruption, indicating a positive association between CBD oil and better sleep.

There are multiple clinical trials testing the effects of CBD oil for sleep in patients with sleep disturbances or diagnosed insomnia. This study using CBD capsules found that 25-75 mg of CBD after dinner improved some scores of sleep quality on the PSQI.

There are a lot of sleep CBD products on the market, but since CBDA oil is new, there are much fewer options to buy and studies assessing CBDA benefits are just starting to be released. 

Since both CBD and CBDA act on the CB2 receptor in the endocannabinoid system, their anxiety and sleep benefits may be similar. 

In this recent study, CBD and CBDA had similar interaction kinetics with CB2 receptors, but CBDA was able to increase expression of CB2 receptors significantly more than CBD.There appears to be significant overlap in the function of CBD and CBDA in the endocannabinoid system. With the enhanced absorption of CBDA compared to CBD, it may be a superior method to modulate the endocannabinoid system to help with better sleep outcomes.

What Makes CBDA Sleep Products Better Than Their CBD Counterparts?

You’re familiar with the idea of using CBD before bed to try and ease your mind and body into a state of bliss, helping you fall asleep – and stay asleep. But it’s becoming more and more clear that CBDA sleep products work better – why is that? 

It all comes down to absorption, interaction with the endocannabinoid system, and the balancing properties of this lesser-known cannabinoid. Here’s why it may be worth taking a shot on CBDA for sleep…

Absorption

Why is this important? New research suggests that the acidic cannabinoids, like CBDA, have unique properties, such as enhanced absorption, which confers substantial benefits for overall health. Recently published clinical data has found that CBDA absorption is over 450% more absorptive than CBD oil.

How well the body absorbs a compound is critical to how much benefit you get from it. Many clinical trials using conventional cannabinoids, such as CBD, have found that you need higher doses to achieve therapeutic properties. 

For example, in this study on reducing anxiety from public speaking, 600mg of CBD oil was needed to relieve symptoms.

Endocannabinoid system

Cannabinoids interact with the body through the endocannabinoid system, and while each one has a few overlapping similarities with the others, they also have unique properties that work in different ways. 

CBD primarily works through the cannabinoid receptor 2 (CB2), and CBDA has recently been shown to as well. In addition, it also was able to increase CB2 receptors while CBD decreased it expression.

The endocannabinoid system has many components in addition to cannabinoid receptors, and one of them is the 5HT1A receptor, commonly associated with serotonin function. The 5HT1A receptor has recently been implicated as the critical target for CBDA in animal models of nausea and anxiety.

A modified CBDA (HU-580; methylated CBDA) and CBDA itself, were able to activate the 5HT1A receptor and prevent signs of anxiety and nausea in an in vivo model. 

The 5HT1A receptor is a common target for antidepressants, specifically the SSRI (selective serotonin reuptake inhibitor) class, since it is involved in regulating serotonin levels in the nervous system.

Anti Inflammatory

Inflammation, activation of the immune system or cellular immunity, is a common underlying process for many pathologies. There is a significant body of research showing how inflammation may disturb sleep function. 

A 2015 study in patients with depression and high inflammation found that inhibiting a common pro-inflammatory cytokine, TNF (tumor necrosis factor), was able to improve sleep. Sleep disturbance is one of the most common reports in patients with depression, and the connection with activation of inflammatory states is a well-noted connection between the two.

The different benefits of CBDA to sleep disturbances may include its unique anti-inflammatory properties. A number of studies are now showing that CBDA can inhibit COX2 (cyclooxygenase 2), a critical enzyme that drives inflammation. 

The COX2 enzyme is widely appreciated for its role in general inflammation processes and is a primary target for a lot of NSAIDs like ibuprofen.

 In fact, anti-inflammatory COX2 inhibitors, such as Celecoxib, have been used with some success to treat depression. Animal models of inflammation and depression found that COX2 inhibition decreased TNF cytokine increase in some parts of the brain.

Further research into the effects of CBDA on inflammation, anxiety, and sleep is needed, but there are potentially interesting mechanisms that could underly its potential benefits.

How to Choose the Best CBDA Sleep Oil

When it comes to selecting CBDA sleep oil or other products, understanding the intricacies of its formulation and the synergy of its components is key. 

The market is flooded with various CBDA products, each claiming superior benefits. However, discerning the best requires a deeper dive into what truly makes a CBDA oil effective for sleep.

Understanding the Entourage Effect in CBDA Oils

The concept of the ‘entourage effect’ is pivotal in the world of cannabinoids. This theory suggests that the combined action of cannabinoids, terpenes, and flavonoids found in full-spectrum or broad-spectrum CBDA oils is more effective than any single compound used in isolation. 

The synergy among these compounds can enhance the overall therapeutic effects, potentially making them more beneficial for sleep.

Full-spectrum CBDA oils contain a range of cannabinoids, including trace amounts of THC, CBD, and other minor cannabinoids. This combination is believed to work in unison, enhancing the oil’s ability to promote relaxation and support a restful sleep cycle.

Several studies back the entourage effect, indicating that a full-spectrum oil could offer enhanced benefits, particularly for sleep disorders. These studies suggest that the presence of multiple cannabinoids and other plant compounds in CBDA oil may lead to improved sleep quality.

Considerations for THC Content

While the presence of THC in CBDA oil can contribute to the entourage effect, it’s crucial to consider its concentration.

THC, even in small quantities, can amplify the sleep-inducing properties of CBDA oil. However, it’s essential to maintain a balance. Excessive THC levels can lead to adverse effects like anxiety or paranoia, particularly in sensitive individuals.

The legal limit for THC content in hemp-derived products is 0.3% by dry weight. When choosing a CBDA oil, ensure that it complies with this regulation. A safe starting dose of THC should not exceed 10mg to avoid potential side effects.

Importance of Certificate of Analysis (CoA)

A CoA is essential in verifying the quality and safety of CBDA products. The CoA provides detailed information about the potency and purity of the product. 

It confirms that the CBDA oil is free from harmful contaminants like pesticides, heavy metals, and solvents, and accurately labeled in terms of cannabinoid content.

Understanding how to read and interpret a CoA is crucial. Natural Dos provides resources to help consumers learn about these aspects, empowering them to make informed choices. 

To see how to read and interpret a cannabinoid CoA, check out our CoA Guide. Otherwise, it’s time you got the best CBDA sleep products at Natural Dos today!

Natural Dos’ Unique Purification Process

Natural Dos has developed a proprietary method to extract Natural Spectrum CBDA oil. This technique ensures that all acidic cannabinoids are retained in their most potent and natural form, offering maximum efficacy.

We offer a diverse range of products each made with this unique extraction process. This variety caters to different preferences and lifestyles, making it easy to incorporate CBDA into your nightly routine.

Every product comes with a full CoA, validating potency and purity of the product – from our CBDA gummies to our CBDA mints

Tips on Using CBDA for Sleep

Before we wrap up our guide on how to use CBDA for sleep, we want to offer a few parting tips on how to actually harness its potential to improve your sleep quality. 

Determining the Right Dosage

Your CBDA dosage is not something to take lightly. CBDA’s higher absorption rate compared to CBD means that smaller doses can be equally effective. This enhanced bioavailability is a significant advantage, as it allows for lower dosages while still achieving desired results.

For new users, a starting dose of 30mg to 50mg of CBDA is recommended. This range is typically sufficient to mirror the effects of a 250mg dose of CBD, owing to CBDA’s superior absorption.

It’s important to listen to your body and adjust the dosage as needed. While 30mg to 50mg is a good starting point, individual responses can vary. 

Incorporating CBDA into Your Nighttime Routine

Consistency is crucial when using CBDA for sleep. Establishing a regular routine enhances the likelihood of experiencing its full benefits.

We recommend taking your CBDA dose 1-2 hours before bedtime. This timing helps prepare your body and mind for sleep, allowing the CBDA to take effect.

For optimal results, incorporate CBDA into your nightly routine for at least two weeks. This duration allows you to assess its effectiveness and make any necessary adjustments.

Choosing the Right CBDA Product Form

The form in which you take CBDA can influence its efficacy, especially concerning absorption rates. CBDA tinctures are often preferred for their rapid absorption. When used sublingually (placed under the tongue for 30 seconds), tinctures bypass the digestive system, allowing the CBDA to enter the bloodstream more directly and quickly.

While tinctures offer fast absorption, CBDA capsules can be a convenient alternative. They provide a pre-measured dose, ensuring consistency in your intake. However, capsules may take longer to take effect as they pass through the digestive system. The same is true of gummies and other edibles.

General Tips on Improving Sleep

Beyond incorporating CBDA sleep products, here is some general sleep advice to consider as well:

  • Establish a Regular Sleep Schedule: Stick to a consistent sleep schedule, even on weekends. Going to bed and waking up at the same time every day helps regulate your body’s internal clock.
  • Create a Restful Environment: Make your bedroom conducive to sleep. Keep it dark, quiet, and cool. Consider using blackout curtains, earplugs, or white noise machines if necessary.
  • Limit Exposure to Screens: Reduce exposure to blue light emitted by phones, tablets, and computers before bedtime. The blue light can disrupt your body’s ability to prepare for sleep.
  • Mindful Eating and Drinking: Avoid large meals, caffeine, and alcohol close to bedtime. These can disrupt sleep patterns and decrease sleep quality.
  • Physical Activity: Regular physical activity can promote better sleep, helping you fall asleep faster and enjoy deeper sleep. However, avoid being too active close to bedtime.
  • Relaxation Techniques: Incorporate relaxation techniques such as deep breathing, meditation, or gentle yoga into your evening routine to help calm your mind.
  • Manage Worries: Try to resolve your worries or concerns before bedtime. Jotting down what’s on your mind can be effective. Practice stress management techniques during the day.
  • Comfortable Bedding: Invest in a comfortable mattress and pillows. The quality of your bedding can impact your sleep.
  • Pre-Sleep Routine: Develop a pre-sleep routine to signal your body it’s time to wind down. This could include reading, taking a warm bath, or listening to soothing music.
  • Limit Daytime Naps: Long daytime naps can interfere with nighttime sleep, especially if you’re struggling with insomnia or poor sleep quality.

Apply these tips along with our CBDA sleep products and you can put insomnia in the past for good! Shop now as we wrap this guide up with a few final thoughts. 

Final Thoughts on CBDA Sleep

That concludes our CBDA sleep guide – we hope you’re able to find relief from sleepless nights through the insights we’ve shared today.

There is a lot of overlap between how well you sleep and anxiety, stress, and inflammation. How your daily routine affects each one separately, and in combination, could provide significant benefit as they all appear to be interconnected.

The CBDA oil benefits for sleep are the subject of ongoing research, but if nothing else, anecdotal evidence shows huge promise for this cannabinoid to eliminate the frustration of insomnia.

If you are on medications and are looking for benefit from CBDA oil, please speak with your physician first. There may be drug-drug interactions for some medications that could affect liver function.

We have similar resources on topics like CBDA for pain, CBDA for nausea, CBDA for depression, CBDA for inflammation, and more. Or, learn about CBDA vs CBG, CBDA side effects, does CBDA make you high, or CBDA vs CBDV.

Colin Reily PhD

Article scientifically and medically reviewed for accuracy. Colin Reily is a Professor of Medicine and scientific consultant.

Recent Posts

CBDA for Pain

CBDA for Pain - The Science Are you experiencing joint pain that's disrupting your daily…

2 months ago

CBDA for Depression

CBDA for Depression Mental wellness can mean a lot of different things, and often, when…

2 months ago

CBDA Coffee: Awaken Your Senses With 8 Surprising Benefits of CBDA-Infused Coffee!

CBDA Coffee: Awaken Your Senses With 8 Surprising Benefits of CBDA-Infused Coffee! Are you looking…

2 months ago

CBDA and Cancer: What Does the Science Say?

The moment cancer enters your life, it brings a shadow of uncertainty and fear. The…

2 months ago

CBDA Flower: Is This the Right Delivery Method For You?

CBDA Flower: Is This the Right Delivery Method For You? We used to think that…

2 months ago